Halbower and colleagues compared MRI images of the brains of 19 children with severe obstructive sleep apnea to 12 children without this disorder. It was apparent from these scans that those children with obstructive sleep apnea had differences in two regions of the brain: the hippocampus, which is integral to learning and memory, and the right frontal cortex, which controls higher-level thinking.
"This is truly concerning because we saw changes that suggest brain injury in areas of the brain that house critical cognitive functions, such as attention, learning and working memory," said Halbower.
To further look at the cognitive effects that obstructive sleep apnea may have on children, the researchers gave each child involved in the study IQ tests to measure verbal, memory and thinking abilities.
The children with obstructive sleep apnea had an average IQ test score of 85, while the children without the disorder scored 101 on average. The children with obstructive sleep apnea also scored lower on tests of verbal abilities.
The interrupted sleep and oxygen deprivation that obstructive sleep apnea causes has already been linked to cardiovascular problems as well as memory deficits in adults. But this is the first time that actual brain damage has been identified in children.
The team hopes to determine if treatment for obstructive sleep apnea will help to reverse the effects of the disorder on the brain. This is important, since parts of the brain continue to mature well past 30 years of age, any damage early on could mean lasting problems for children with the disorder.