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Thyroid Health Hypothyroidism

Hypothyroidism


Medically Reviewed On: July 11, 2006

Summary

Also known as “underactive thyroid,” hypothyroidism is a disorder in which the thyroid gland does not produce enough thyroid hormone to meet the body's needs. A lack of thyroid hormone can cause a variety of symptoms affecting most of the body's major systems. These symptoms might include fatigue, weakness, lack of appetite and a low sex drive.

Hypothyroidism can be caused various factors. The most common cause in the United States is a disease called Hashimoto disease, in which the body's own immune system targets and destroys thyroid cells. It can also be caused by problems with the pituitary gland, which regulates function of the thyroid gland, as well as birth defects, surgical removal of the thyroid gland, irradiation of the neck or inflammation of the thyroid gland. Because the range of symptoms in hypothyroidism is so wide, it can be difficult for physicians to diagnose.

Generally, hypothyroidism is diagnosed with laboratory tests that measure the level of thyroid hormone and thyroid-stimulating hormone (TSH), which is responsible for causing the thyroid to increase production of thyroid hormone. In cases of hypothyroidism caused by problems with the thyroid gland itself, the TSH level will be elevated while the level of thyroid hormone is reduced. This reflects the body's attempts to stimulate the thyroid to secrete more hormone.

Hypothryoidism is also frequently classified into subclinical hypothyroidism and overt hypothyroidism. In cases of subclinical hypothryoidism, the level of TSH is elevated but the level of thyroid hormone may be normal. These patients may have only very slight symptoms or none at all. In overt hypothyroidism, TSH will be elevated and thyroid hormone levels are depressed. These patients are likely to have symptoms and signs consistent with hypothyroidism.

The majority of people with hypothyroidism will need to take manufactured versions of natural thyroid hormones for the rest of their lives to relieve their symptoms and to avoid serious long–term consequences. These consequences include a greater risk for hardening of the arteries (atherosclerosis), heart disease, heart attack, high blood pressure (hypertension), stroke, respiratory problems and anemia.

About hypothyroidism

Also known as “underactive thyroid,” hypothyroidism is a disorder in which the thyroid gland is not producing enough thyroid hormone to meet the body's needs. It is much more common than hyperthyroidism, in which too much thyroid hormone is produced.

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